About the Company
Pfizer is a global biopharmaceutical company committed to discovering and developing innovative medicines and vaccines. Our purpose is to bring breakthroughs that change patients’ lives. With a legacy of over 170 years, we are at the forefront of medical innovation, addressing some of the world’s most challenging health issues, including a strong focus on oncology. Join our team in Lake Nona, a vibrant medical and research hub, and contribute to cutting-edge science that truly makes a difference.
Job Description
We are seeking a highly motivated and skilled Oncology Research Chemist to join our dynamic R&D team in Lake Nona. In this crucial role, you will contribute to the discovery and development of novel small molecules targeting various cancers. You will be responsible for designing, synthesizing, and characterizing new chemical entities, as well as developing and optimizing synthetic routes. This position offers a unique opportunity to work on meaningful projects that directly impact patient outcomes, collaborating with cross-functional teams of biologists, pharmacologists, and computational chemists. If you are passionate about applying your chemistry expertise to solve complex challenges in oncology and are looking for a comprehensive package of benefits and career growth, we encourage you to apply.
Key Responsibilities
- Design and execute multi-step organic syntheses of novel small molecules for oncology targets.
- Develop and optimize efficient synthetic routes to prepare target compounds.
- Purify and characterize synthesized compounds using standard analytical techniques (NMR, MS, HPLC, etc.).
- Analyze and interpret analytical data to confirm compound identity and purity.
- Collaborate closely with medicinal chemists, biologists, and other scientists in a team-oriented environment.
- Maintain accurate records of experiments, data, and results in electronic laboratory notebooks.
- Present research findings effectively in internal team meetings and to broader scientific audiences.
- Stay current with scientific literature and new technologies in synthetic organic chemistry and oncology.
- Contribute to the preparation of patent applications and scientific publications.
Required Skills
- Ph.D. in Organic Chemistry or Medicinal Chemistry with 3+ years of post-doctoral or industry experience, OR M.S. with 5+ years of relevant industry experience.
- Demonstrated expertise in multi-step organic synthesis, reaction mechanism, and retrosynthetic analysis.
- Proficiency in purification techniques (e.g., column chromatography, recrystallization) and analytical methods (e.g., NMR, MS, HPLC).
- Strong problem-solving skills and ability to troubleshoot synthetic challenges.
- Excellent written and verbal communication skills.
- Ability to work effectively both independently and as part of a collaborative team.
Preferred Qualifications
- Experience in drug discovery and development, particularly in an oncology therapeutic area.
- Familiarity with computational chemistry tools for compound design and property prediction.
- Knowledge of ADMET principles and their application in lead optimization.
- Track record of scientific contributions (publications, presentations, patents).
Perks & Benefits
- Competitive base salary and annual performance bonus.
- Comprehensive health, dental, and vision insurance plans.
- Generous paid time off and holidays.
- 401(k) retirement plan with company match.
- Tuition reimbursement and professional development opportunities.
- On-site fitness center and wellness programs.
- Employee assistance program.
- Opportunities for career advancement in a leading global company.
How to Apply
If you are interested in this position, please click the "Apply Now" button below. To ensure your application is properly considered, please prepare the following:
- An up-to-date Resume or CV
- A brief cover letter summarizing your experience and motivation
Applications are reviewed on a rolling basis. Only shortlisted candidates will be contacted for an interview.
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