About the Company
Amgen is a leading global biotechnology company committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing, and delivering innovative human therapeutics. With a presence in over 100 countries, our pioneering work in areas like oncology, neuroscience, and inflammation has transformed the lives of millions. Join us in Boulder, CO, where cutting-edge science meets a vibrant community, as we continue to push the boundaries of what’s possible in medicine.
Job Description
We are seeking a highly motivated and skilled Pharmaceutical Chemist to join our dynamic High-End Biotech team in Boulder, Colorado. This role is crucial for advancing our innovative drug discovery and development pipeline. The successful candidate will play a pivotal role in the synthesis, purification, and characterization of novel chemical entities, contributing directly to the creation of life-changing therapies. If you are passionate about applying your chemistry expertise in a fast-paced, collaborative, and impactful environment, with the added benefit of a sign-on bonus, we encourage you to apply.
Key Responsibilities
- Design and execute multi-step organic synthesis of small molecules for drug discovery programs.
- Purify synthesized compounds using various chromatographic techniques (e.g., flash chromatography, HPLC).
- Characterize compounds using advanced analytical instrumentation, including NMR, MS, and IR.
- Interpret complex analytical data to confirm compound identity and purity.
- Maintain detailed and accurate laboratory notebooks and electronic records.
- Collaborate effectively with medicinal chemists, biologists, and other cross-functional teams.
- Contribute to the optimization of synthetic routes and reaction conditions.
- Ensure strict adherence to laboratory safety protocols and best practices.
- Present research findings in team meetings and contribute to scientific reports.
Required Skills
- Ph.D. in Organic Chemistry, Medicinal Chemistry, or a related field; or a Master’s degree with 3+ years of relevant experience; or a Bachelor’s degree with 5+ years of relevant experience.
- Demonstrated expertise in synthetic organic chemistry, including reaction design, execution, and work-up.
- Proficiency in operating and interpreting data from analytical instruments such as NMR, LC-MS, and HPLC.
- Strong problem-solving skills and ability to troubleshoot synthetic challenges.
- Excellent written and verbal communication skills.
- Ability to work both independently and as part of a collaborative team.
- Meticulous attention to detail and strong organizational skills.
Preferred Qualifications
- Postdoctoral experience in an academic or industrial setting.
- Experience in a pharmaceutical or biotechnology industry environment.
- Familiarity with parallel synthesis and automation techniques.
- Knowledge of drug discovery principles and lead optimization strategies.
- Experience working in a GLP/GMP compliant laboratory setting.
Perks & Benefits
- Competitive base salary and annual performance bonus.
- Generous sign-on bonus.
- Comprehensive health, dental, and vision insurance plans.
- 401(k) retirement plan with company matching contributions.
- Paid time off, including vacation, holidays, and sick leave.
- On-site fitness center and wellness programs.
- Professional development and continuing education opportunities.
- Employee stock purchase program.
- Relocation assistance for eligible candidates.
How to Apply
If you are interested in this position, please click the "Apply Now" button below. To ensure your application is properly considered, please prepare the following:
- An up-to-date Resume or CV
- A brief cover letter summarizing your experience and motivation
Applications are reviewed on a rolling basis. Only shortlisted candidates will be contacted for an interview.
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